CHEMOTHERAPEUTIC AGENTS

⭐ CHEMOTHERAPEUTIC AGENTS

📌 POINTS TO PONDER

🔹Pin Cushion Effect- One charged end of chlorhexidine (CHX) molecule binding to the tooth surface and the other remaining available to interact with bacterial membrane as microorganism approaches the tooth surface as pin-cushion effect.

🔹Substantivity of CHX is around 12 hrs.

🔹Substantivity of Triclosan is around 5 hrs.

🔹Substantivity of Cetylpyridium is around 3-5 hrs.

🔹Chemotherapeutic agents used as premedication in periodontal surgery are anxiolytics, antibiotics,antiseptics and NSAIDs.

🔹Three groups of antimicrobials which interfere with food absorption are tetracyclines, quinolones and azithromycin.